POS0797-HPR PREVALENCE AND ASSOCIATIONS WITH DEVELOPMENT OF RADIOGRAPHIC KNEE OSTEOARTHRITIS IN INDIVIDUALS WITH KNEE PAIN – A 2-YEAR FOLLOW-UP

Background Pain and functional impairment form the basis for a clinical knee osteoarthritis (KOA) diagnosis according to National Institute Health Care Excellence (NICE) guidelines [1]. Enhanced knowledge of progression from pain radiographic KOA (RKOA), may enable early identification individuals at risk. Objectives To study development in with over time, its associations baseline variables. Methods In all 172 (30-67 years) pain, Swedish HALLOA cohort (2) were studied 2-year follow-up. The coded as NICE or not. None had RKOA baseline. At follow-up they dichotomised not (Ahlbäck grade 1 more). Self-reported symptoms (the Knee injury Osteoarthritis Outcome Score (KOOS)), intensity (numerical rating scale (NRS)) assessed. Body composition, performance examination also Chi-Square-test Mann-Whitney U-test was used comparisons between groups, logistic regression analysis variables adjusted age. Results mean age group 51 (SD 8) years, 67% women, Mass Index (BMI) 26 5). prevalence 13% (n=23), them guidelines. Furthermore, those significantly higher BMI median 28.8 (IQR 8.6) vs. 25.1 (5.7), p=0.011, visceral fat area (VFA) 130.7 (88.7) 84.7 (62.4), p=0.009, pain; KOOS sub score 69 (28) 78 (19), p=0.016, 5.0 (5.0) 4.0, (3.0) p=0.039, Higher VFA, worse intensity, scores Pain, Symptoms, ADL, QOL baseline, associated (Table 1). Sex, self-reported morning stiffness restricted motion, tests examined crepitus, thus included final (p-value 0.477 - 0.930). Conclusion More than one out ten developed already 2 years. can be detected through guidelines, assessment BMI, VFA questionnaire support start management. References [1]National Clinical Excellence. 16s: 2022. [2]M. L. E. Andersson et al. profile. BMJ open 2022 Table 1. Development more painful knee) (n=172), analysed models Odds ratio (OR) 95% CI p-value (kg/m ) 1.132 1.034-1.240 0.007 Visceral ( cm 1.009 1.001-1.018 0.024 (NRS 0-10, best worst 1.230 1.022-1.480 0.028 Bony enlargement 1.788 0.683-4.686 0.237 One-Leg Rising, (number 0.966 0.921-1.012 0.146 (Pain 0-100, 0.964 0.937-0.991 0.011 (Symptoms, 0.968 0.940-0.996 (ADL, 0.969 0.941-0.998 0.039 (Sport/Rec, 0.984 0.966-1.002 0.088 (QOL, 0.970 0.944-0.997 0.030 NRS = Numeric Rating Scale intensity. Score. ADL Function, daily living. Sport/Rec sports recreational activities. Quality Life. Acknowledgements: NIL. Disclosure Interests Declared.